About This Spot

Stepping into Mario’s Mexican Grille & Cantina feels like entering a lively neighborhood gathering spot where warmth and familiarity fill the air. The pace is unhurried yet vibrant, inviting you to settle in and savor not just a meal, but a moment of connection. The friendly greetings from Mario himself, who often makes his rounds with a genuine smile, set the tone—this is a place that values community, warmth, and the simple pleasure of sharing good food.

The atmosphere balances the casual with the colorful, reflecting an authentic Mexican spirit right in the heart of Greer. Bright accents and inviting aromas mingle as familiar sounds of laughter and conversation rise around you. It’s the kind of place where tables are filled with families, friends, and neighbors, creating a mosaic of shared stories and quiet celebrations.

Here, dishes arrive as part of an experience that honors tradition and generous hospitality. Whether you’re drawn to a heaping plate of sizzling fajitas, the comforting richness of enchiladas, or the fresh, tangy bite of street corn, you’ll find that each offering feels thoughtfully made. There’s a careful balance of flavors that invites you to slow down, explore each ingredient, and savor the unpretentious joy of authentic Mexican cooking crafted with care.

Mario’s also embraces families and first-time visitors with an attentive approach that makes everyone feel welcomed. The team’s gentle attentiveness—checking in with genuine interest, accommodating special requests without fuss—helps the restaurant feel less like a stop on your day and more like a return to a favorite local gathering place.

Beyond just a meal, Mario’s is a space where meals become memories, where the simple acts of sharing chips and salsa or enjoying a refreshing drink carry a comforting familiarity. It's not just about food; it's about the moments that unfold naturally, as flavorful and genuine as the dishes they serve.

What’s Available Here

  • IconKerbside pickup
  • IconTakeaway
  • IconDine-in
  • IconDelivery
  • IconFast service
  • IconGreat beer selection
  • IconGreat cocktails
  • IconServes local specialty
  • IconLunch
  • IconDinner
  • IconSolo dining
  • IconWheelchair-accessible car park
  • IconWheelchair-accessible entrance
  • IconWheelchair-accessible seating
  • IconWheelchair-accessible toilet
  • IconAlcohol
  • IconBeer
  • IconCocktails
  • IconCoffee
  • IconComfort food
  • IconQuick bite
  • IconSmall plates
  • IconSpirits
  • IconWine
  • IconBreakfast
  • IconLunch
  • IconDinner
  • IconCatering
  • IconDessert
  • IconSeating
  • IconTable service
  • IconBar on site
  • IconToilet
  • IconWi-Fi
  • IconWi-Fi
  • IconCasual
  • IconQuiet
  • IconGroups
  • IconTourists
  • IconAccepts reservations
  • IconCredit cards
  • IconDebit cards
  • IconNFC mobile payments
  • IconGood for kids
  • IconHigh chairs
  • IconKids' menu
  • IconFree of charge street parking
  • IconFree parking lot
  • IconParking

Location & Hours

Monday 11:00 AM - 09:00 PM
Tuesday 11:00 AM - 09:00 PM
Wednesday 11:00 AM - 09:00 PM
Thursday 11:00 AM - 09:00 PM
Friday 11:00 AM - 10:00 PM
Saturday 11:00 AM - 10:00 PM
Sunday 11:00 AM - 09:00 PM

Guest Reviews

Chandler Hyatt 05 Jan 2026

Mario’s is one of those rare gems where the food is always great, the atmosphere is warm and welcoming, and the service makes you feel like family. The owner is incredibly kind and personally greets guests at the door, often stopping by each table to say thank you. He’ll even say “See you tomorrow” with a smile, and honestly, you just might come back that soon. A true local favorite.

Paul Miller 07 Dec 2025

First time last Saturday. Food was very good, and came to the table promptly. The service was fantastic. Mario and his staff do a great job. Will return. In the picture, my wife has pollo loco and I had the burrito California.

Elia W 06 Dec 2025

My family and I stopped by to grab some lunch after church, and we were pleasantly surprised by our experience! The staff is very friendly and accommodating, making sure to check on us and refilling our drinks! Our food came out quickly, and everyone was stuffed when we left! My daughter ordered from the kids' menu and settled on mac and cheese, and my son had the shrimp enchiladas. (One of our favorites) I ordered the camarones diablo (spicy shrimp in a red sauce), and they delivered on the heat! The complimentary chips and salsa were wonderful. The hotter version had great flavor, and some kick! Is it a traditional Mexican restaurant??? I wouldn't call it that, but it was a good alternative if you're craving this cuisine.

Laurie D 15 Oct 2025

Excellent food and service! Mario is always walking around checking on guests. Food is delicious! Queso is so good and thick! As far as the reviewer that said “special requests” don’t happen I am here to tell you that is absolutely not true in our case. We have been several times in the past few weeks and I always modify my order and not only do they not charge for special requests they have never got it wrong. We just discovered this place a few weeks ago and visit at least once a week. This is now our go to restaurant when we go out for Mexican!

Beth Scott 07 Oct 2025

Sophia is the best server, super sweet! The owner is very friendly each time and corrected the one thing that was wrong really fast! Very good food! The best we've had in SC! This should be on trip advisors lists instead of buffet type, bland American food. Go try it. And take a photo with the angel wings too. I forgot the other pictures, but so good.

Colin Hambrook 21 Sep 2025

If you haven’t been to Mario’s Mexican Grille in Greer yet, you are seriously missing out. Every single visit reminds me why this place is hands-down my favorite Mexican restaurant. The food is consistently incredible; it’s fresh, flavorful, and clearly made with care. Whether you’re craving the classics or something a little more unique, they nail it every time. The waitstaff is just as amazing as the food. They’re friendly, fun, and make you feel like you’ve been coming there for years, even if it’s your first time. The whole vibe is relaxed and welcoming, and the service is always on point. If you’re looking for great food, cool people, and the best Mexican experience in Greer, Mario’s is the move. Highly recommend!!

Scott Tulk 18 Sep 2025

Great little restaurant! Friendly staff too. I tried one of the lunch specials on the menu. It was one potato and one shredded beef Burrito. Both were good, but the beef was especially good! Salas were good, could have been chunkier for my personal preference. I'll definitely stop back in for lunch again.

Cyndi Gionfriddo 16 Sep 2025

Amazing & flavorful food, great staff, clean & great atmosphere. 1st visit & it did not disappoint. The food was authentic and flavorful. The staff was so welcoming & wonderful. We had a great experience. The guacamole is amazing! Shrimp tacos were incredible & full of flavor.

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